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“Shedding” light on HER4 signaling in normal and malignant breast tissues

9 Jul 2022

Abstract excerpt

Receptor Tyrosine Kinases of the Epidermal Growth Factor Receptor Family play a pivotal role as drivers of carcinogenesis and uncontrolled cell growth for a variety of malignancies, not least for breast cancer. Besides the estrogen receptor, the HER2 receptor was and still is a representative marker for advanced taxonomic sub-differentiation of breast cancer and emerged as one of the first therapeutic targets for...

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PMID: 35820544
DOI: 10.1016/j.cellsig.2022.110401

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