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Different phylotypes of Cutibacterium acnes cause different modic changes in intervertebral disc degeneration

12 Jul 2022

Abstract excerpt

BACKGROUND: The contribution of Cutibacterium acnes (C. acnes) infection to intervertebral disc degeneration (IDD) and the antibiotic therapy has evoked several controversies in recent years. While some microbiology studies report bacterial disc infection within IDD patients, others attribute the positive results to contamination during prolonged cultures. In addition to the clinical controversy, little was known...

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PMID: 35819943
DOI: 10.1371/journal.pone.0270982

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