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New Insights Link Low-Virulent Disc Infections to the Etiology of Severe Disc Degeneration and Modic Changes

1 Jun 2019

Abstract excerpt

Within the last 5 years, international research collaborations including those of several research groups skilled in microbiology, immunology and pathophysiology, have identified a low-virulent intradiscal infection with the ability to provoke gradual and progressive disc degeneration, end-plate disruption, Modic changes and persistent clinical lower-back pain. Certain strains of the Propionibacterium acne...

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PMID: 31245043
DOI: 10.2144/fsoa-2019-0022

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