Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lrig1- and Wnt-dependent niches dictate segregation of resident immune cells and melanocytes in murine tail epidermis

11 Jul 2022

Abstract excerpt

The barrier-forming, self-renewing mammalian epidermis comprises keratinocytes, pigment-producing melanocytes and resident immune cells as first-line host defense. In murine tail skin, interfollicular epidermis patterns into pigmented 'scale' and hypopigmented 'interscale' epidermis. Why and how mature melanocytes accumulate in scale epidermis is unresolved. Here, we delineate a cellular hierarchy among epidermal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatology and Skin Diseases
Share to melanin and skin pigmentation
Share to Skin Protection and Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35815643
DOI: 10.1242/dev.200154

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lrig1- and Wnt-dependent niches dictate segregation of resident immune cells and melanocytes in murine tail epidermisPMID 35815643Read ↗

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.Semantic proximity Read ↗

Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine ApplicationsSemantic proximity Read ↗

Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian EpidermisSemantic proximity Read ↗

Cutaneous inflammation accelerates the premalignant expansion of melanocytes bearing oncogenic mutationsSemantic proximity Read ↗

Dedicated epithelial recipient cells determine pigmentation patterns.Semantic proximity Read ↗

Skin-resident immune cells actively coordinate their distribution with epidermal cells during homeostasisSemantic proximity Read ↗

IFN-γ signaling maintains skin pigmentation homeostasis through regulation of melanosome maturationSemantic proximity Read ↗

Ontogeny and function of murine epidermal Langerhans cells.Semantic proximity Read ↗

Developmentally programmed early-age skin localization of iNKT cells supports local tissue development and homeostasisSemantic proximity Read ↗

Covering the limb – formation of the integumentSemantic proximity Read ↗

Early skin seeding regulatory T cells modulate PPARγ-dependent skin pigmentationSemantic proximity Read ↗

Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair FollicleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.