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Quantitative morphokinetic parameters identify novel dynamics of oocyte meiotic maturation and cumulus expansion

8 Jul 2022

Abstract excerpt

Meiotic maturation and cumulus expansion are essential for the generation of a developmentally competent gamete, and both processes can be recapitulated in vitro. We used a closed time-lapse incubator (EmbryoScope+™) to establish morphokinetic parameters of meiotic progression and cumulus expansion in mice and correlated these outcomes with egg ploidy. The average time to germinal vesicle breakdown (GVBD), time...

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PMID: 35810327
DOI: 10.1093/biolre/ioac139

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