Article

Ovarian support cell in vitro maturation (OSC-IVM) results in healthy murine live births with no evidence of reprotoxicology in a multigenerational study

2024-04-06

Abstract excerpt

<h4>Study question</h4> Does application of human stem cell-derived ovarian support cells (OSCs) for in vitro maturation (IVM) have a safe reproductive toxicity profile? <h4>Summary answer</h4> The use of OSC-IVM co-culture improves blastocyst formation in a mouse model and results in healthy live births with no evidence of reprotoxicity. <h4>What is known already</h4> Abbreviated stimulation to obtain immatu...

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Literature Corpus work: 6ab25195-0473-58de-92ed-6e408b822307
DOI: 10.1101/2024.04.04.588122

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