Article
Identification of genetic variants of the IL18R1 gene in association with COPD susceptibility.
Annals of medicine - 1 Dec 2025
Xu Jiaoyuan, Xian Meilan, Huang Linhui, Zheng Yamei, Zhang Lei, Zhao Jie, Chen Jie, Li Siguang, Lin Lingsang, Zhong Yi, Yang Zehua, Wu Haihong, Xie Tian, Ding Yipeng
Abstract excerpt
BACKGROUND: Although existing studies have identified some genetic loci associated with chronic obstructive pulmonary disease (COPD) susceptibility, many variants remain to be discovered. The aim of this study was to further explore the potential relationship between IL18R1 single nucleotide polymorphisms (SNPs) and COPD risk. METHODS: Nine hundred and ninety-six subjects were recruited (498 COPD cases and 498...
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