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Article

Peripheral Ion Channel Gene Screening in Painful- and Painless-Diabetic Neuropathy

28 Jun 2022

Abstract excerpt

Neuropathic pain is common in diabetic peripheral neuropathy (DN), probably caused by pathogenic ion channel gene variants. Therefore, we performed molecular inversion probes-next generation sequencing of 5 transient receptor potential cation channels, 8 potassium channels and 2 calcium-activated chloride channel genes in 222 painful- and 304 painless-DN patients. Twelve painful-DN (5.4%) patients showed...

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PMID: 35806193
DOI: 10.3390/ijms23137190

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