Article
Painful and painless channelopathies.
The Lancet. Neurology - 1 Jun 2014
Bennett David L H, Woods C Geoffrey
Abstract excerpt
The discovery of genetic variants that substantially alter an individual's perception of pain has led to a step-change in our understanding of molecular events underlying the detection and transmission of noxious stimuli by the peripheral nervous system. For example, the voltage-gated sodium ion channel Nav1.7 is expressed selectively in sensory and autonomic neurons; inactivating mutations in SCN9A, which...
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