Article
Low-grade serous carcinoma detected from intraoperative peritoneal washings: Cytological findings and detection of KRAS mutation.
Cancer reports (Hoboken, N.J.) - 1 Oct 2022
Yamamoto Eriko, Warigaya Kenji, Kinoshita Yuichi, Yamamoto Ayana, Murata Shin-Ichi
Abstract excerpt
BACKGROUND: Low-grade serous carcinoma (LGSC) of the ovary, which is extremely rare tumor, has better prognosis than high-grade serous carcinoma (HGSC). Genetic backgrounds of those are different, so that LGSC usually shows KRAS or BRAF mutation, whereas HGSC does not show such mutations. Since treatment strategies of those are different, differential pathological diagnosis between LGSC and HGSC is very...
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