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Article

High-grade and low-grade pelvic serous neoplasms demonstrate differential p53 immunoreactivity in peritoneal washings.

Acta cytologica - 1 Jan 2011

Chang Martin C, Cibas Edmund S, Crum Christopher P, Kindelberger David W

Abstract excerpt

OBJECTIVE: Serous neoplasms of the female pelvis share a müllerian phenotype. Unlike low-grade serous neoplasms (LGSNs), high-grade serous carcinomas (HGSCs) commonly display p53 mutations. The current study correlates p53 immunoreactivity in peritoneal washings with the cytologic interpretation and histology of the corresponding serous neoplasm. STUDY DESIGN: Peritoneal washings from consecutive cases of pelvic...

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PMID: 21135526
DOI: 10.1159/000320862

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