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Article

Familial pancreatic cancer: genetic advances.

Genes & development - 1 Jan 2014

Rustgi Anil K

Abstract excerpt

Beset by poor prognosis, pancreatic ductal adenocarcinoma is classified as familial or sporadic. This review elaborates on the known genetic syndromes that underlie familial pancreatic cancer, where there are opportunities for genetic counseling and testing as well as clinical monitoring of at-risk patients. Such subsets of familial pancreatic cancer involve germline cationic trypsinogen or PRSS1 mutations...

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Source

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Identifiers

PMID: 24395243
DOI: 10.1101/gad.228452.113
PMCID: PMC3894408

Genes

BRCA2
ATM
PALB2
PRSS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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