Article
Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression
20 Jun 2022
Abstract excerpt
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD), one of the most common human monogenic diseases, is characterized by the presence of numerous fluid-filled renal cysts and is a leading cause of end-stage renal disease (ESRD). Urinary biomarkers may be useful for predicting the variable course of ADPKD progression from cyst growth to ESRD. METHODS: To identify candidate urinary biomarkers of ADPKD...
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