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Article

New treatment paradigms for ADPKD: moving towards precision medicine.

Nature reviews. Nephrology - 1 Dec 2017

Lanktree Matthew B, Chapman Arlene B

Abstract excerpt

The natural history of autosomal dominant polycystic kidney disease (ADPKD) is characterized by a variable rate of cyst development and increase in total kidney volume (TKV), variable kidney function decline and age of onset of end-stage renal disease (ESRD), and variable presentation of renal and extrarenal manifestations. Precision medicine is proposed to improve patient outcomes by tailoring therapy to the...

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Identifiers

PMID: 28989174
DOI: 10.1038/nrneph.2017.127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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