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Article

Clinical features of superficial esophagus squamous cell carcinoma according to alcohol-degrading enzyme ADH1B and ALDH2 genotypes.

Journal of gastroenterology - 1 Sept 2022

Tajiri Ayaka, Ishihara Ryu, Sakurai Hirohisa, Nakamura Takahiko, Tani Yasuhiro, Inoue Takahiro, Matsueda Katsunori, Miyake Muneaki, Waki Kotaro, Fukuda Hiromu, Shichijo Satoki, Maekawa Akira, Kanesaka Takashi, Yamamoto Sachiko, Takeuchi Yoji, Higashino Koji, Uedo Noriya, Michida Tomoki, Matsunaga Takashi

Abstract excerpt

BACKGROUND: Inactivated alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are related to esophageal carcinogenesis. We aimed to clarify the clinical features associated with the alcohol-degrading enzyme genotypes, ADH1B and ALDH2. We also investigated the risk factors for metachronous esophageal squamous cell carcinoma (ESCC) and head and neck SCC (HNSCC). METHODS: We conducted a single-center,...

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Share to Alcohol Dehydrogenase
Share to Aldehyde Dehydrogenase, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 35788888
DOI: 10.1007/s00535-022-01892-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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