Article
Association between interleukin 10 (IL-10) polymorphisms and leishmaniasis progression: a systematic review and meta-analysis.
Scientific reports - 1 Jul 2022
da Silva Renata Rocha, Vasconcelos Fernanda de Santana Fontes, Tavares Débora Dos Santos, Dos Santos Priscila Lima
Abstract excerpt
Interleukin 10 (IL-10) is associated with the progression of leishmaniasis because it inhibits the leishmanicidal action of macrophages and the production of mediators such as IFN-γ and nitric oxide. Studies have shown that specific polymorphisms are associated with the regulatory role of IL-10 and the development of more relevant clinical forms of leishamaniasis. We performed a systematic review and...
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