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Article

Interleukine-22 gene variants are associated with susceptibility to visceral leishmaniasis.

Experimental parasitology - 1 Jan 2000

Kalani Mehdi, Shams Seyed Reza, Namdarnia Sadaf, Choopanizadeh Maral, Jamshidi Javad, Moravej Ali

Abstract excerpt

Visceral leishmaniasis (VL) is an infectious disease caused by an intracellular protozoan belonging to Leishmania species. Interleukin (IL)-22 plays an important role in inflammatory response, chemotaxis, regulation of cellular proliferation and tissue repair. Considering the role of IL-22 in control of leishmaniasis and the effect of its single nucleotide polymorphisms (SNPs) on respective function and...

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PMID: 34115995
DOI: 10.1016/j.exppara.2021.108122

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