Article
Analysis of polymorphisms in EGF, EGFR and HER2 genes in pancreatic neuroendocrine tumors (PNETs).
Cancer genetics - 1 Aug 2022
Marinović Sonja, Cigrovski Berković Maja, Zjačić-Rotkvić Vanja, Kapitanović Sanja
Abstract excerpt
OBJECTIVES: Pancreatic neuroendocrine tumors (NETs) are rare and account for about 7% of all cancers occurring in the pancreas. The epidermal growth factor family of receptors and their ligands play an important role in the growth and progression of tumors but their role in PNET development remains unknown. We hypothesized that functional single nucleotide polymorphisms (SNPs) in the EGF, EGFR, and HER2 genes...
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