Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular characterization of the pig C3 gene and its association with complement activity.

Immunogenetics - 1 Jan 2003

Wimmers Klaus, Mekchay Supamit, Schellander Karl, Ponsuksili Siriluck

Abstract excerpt

The complement system catalyzes direct lysis of micro-organisms and modulates phagocytosis, inflammation, humoral and cellular immune responses. Since the complement protein C3 is the central component within all pathways of complement activation, C3 is a candidate gene for complement activity and also for improved protection against many pathogens. The pig C3 gene was sequenced, screened for polymorphisms, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Complement C3
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Herpesvirus 1, Suid

Share to Promoter Regions, Genetic

Share to RNA, Messenger

Share to Vaccination

Source

Identifiers

PMID: 12557058
DOI: 10.1007/s00251-002-0524-y

Genes

C3
HP
F2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular characterization of the pig C3 gene and its association with complement activity.PMID 12557058Read ↗

Association of the porcine C3 gene with haemolytic complement activity in the pig.Semantic proximity Read ↗

Molecular cloning and sequencing of porcine C5 gene and its association with immunological traits.Semantic proximity Read ↗

Complement component 3 haplotypes influence serum complement activity and milk production traits in Chinese Holstein cattle.Semantic proximity Read ↗

Hereditary Deficiency of C3 in Animals and HumansSemantic proximity Read ↗

BF, HP, DQB and DRB are associated with haemolytic complement activity, acute phase protein reaction and antibody response in the pig.Semantic proximity Read ↗

Complement C3 and its polymorphism: biological and clinical consequences.Semantic proximity Read ↗

Case Report: A novel homozygous splice-site variant in the C3 gene causing complete complement C3 deficiency in two unrelated Moroccan patients.Semantic proximity Read ↗

The Relationship between Complement Components C1R and C5 Gene Polymorphism and the Values of Blood Indices in Suckling Piglets.Semantic proximity Read ↗

Nonstructural Protein 1 of Variant PEDV Plays a Key Role in Escaping Replication Restriction by Complement C3Semantic proximity Read ↗

Specific Evolution and Gene Family Expansion of Complement 3 and Regulatory Factor H in FishSemantic proximity Read ↗

The Evolution and Appearance of C3 Duplications in Fish Originate an Exclusive Teleost c3 Gene Form with Anti-Inflammatory ActivitySemantic proximity Read ↗

Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.