Article
Circulating tumor DNA predicts outcome in metastatic gastroesophageal cancer.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Sept 2022
van Velzen Merel J M, Creemers Aafke, van den Ende Tom, Schokker Sandor, Krausz Sarah, Reinten Roy J, Dijk Frederike, van Noesel Carel J M, Halfwerk Hans, Meijer Sybren L, Mearadji Banafsche, Derks Sarah, Bijlsma Maarten F, van Laarhoven Hanneke W M
Abstract excerpt
BACKGROUND: Circulating tumor DNA (ctDNA) has predictive and prognostic value in localized and metastatic cancer. This study analyzed the prognostic value of baseline and on-treatment ctDNA in metastatic gastroesophageal cancer (mGEC) using a region-specific next generation sequencing (NGS) panel. METHODS: Cell free DNA was isolated from plasma of patients before start of first-line palliative systemic treatment...
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