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Circulating Tumor DNA Sequencing Analysis of Gastroesophageal Adenocarcinoma

19 Aug 2019

Abstract excerpt

Abstract Purpose: Gastroesophageal adenocarcinoma (GEA) has a poor prognosis and few therapeutic options. Utilizing a 73-gene plasma-based next-generation sequencing (NGS) cell-free circulating tumor DNA (ctDNA-NGS) test, we sought to evaluate the role of ctDNA-NGS in guiding clinical decision-making in GEA. Experimental Design: We evaluated a large cohort (n = 2,140 tests; 1,630 patients) of ctDNA-NGS results...

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PMID: 31427281
DOI: 10.1158/1078-0432.ccr-19-1704

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