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EGR1 Upregulation during Encephalitic Viral Infections Contributes to Inflammation and Cell Death

2 Jun 2022

Abstract excerpt

Early growth response 1 (EGR1) is an immediate early gene and transcription factor previously found to be significantly upregulated in human astrocytoma cells infected with Venezuelan equine encephalitis virus (VEEV). The loss of EGR1 resulted in decreased cell death but had no significant impact on viral replication. Here, we extend these studies to determine the impacts of EGR1 on gene expression following...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35746681
DOI: 10.3390/v14061210

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