Mitochondria, telomeres and cell senescence: Implications for lung ageing and disease

Abstract excerpt

Cellular senescence, the irreversible loss of replicative capacity in somatic cells, plays a causal role in the development of age-related pathology and in a number of age-related chronic inflammatory diseases. The ageing lung is marked by an increasing number of senescent cells, and evidence is mounting that senescence may directly contribute to a number of age-related respiratory diseases, including chronic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Neonatal Respiratory Health Research
• Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
• Share to Telomeres, Telomerase, and Senescence