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Gene network Analysis Defines a Subgroup of Small Cell Lung Cancer patients With Short Survival.

Clinical lung cancer - 1 Sept 2022

Cucchiara Federico, Petrini Iacopo, Passaro Antonio, Attili Ilaria, Crucitta Stefania, Pardini Eleonora, de Marinis Filippo, Danesi Romano, Del Re Marzia

Abstract excerpt

BACKGROUND: Small cell lung cancer (SCLC) is an aggressive tumor, and despite its sensitivity to chemotherapy and radiotherapy, patients usually have a short survival. There are no clinically relevant predictive factors of responses to therapies, and therapeutic options are still limited. MATERIALS AND METHODS: Clinical data and somatic mutations of genes included in the MSK-IMPACT panel were retrieved from...

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PMID: 35739016
DOI: 10.1016/j.cllc.2022.05.012

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