Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction

Abstract excerpt

BACKGROUND: Current clinical therapy of non-small cell lung cancer depends on histo-pathological classification. This approach poorly predicts clinical outcome for individual patients. Gene expression profiling holds promise to improve clinical stratification, thus paving the way for individualized therapy. METHODOLOGY AND PRINCIPAL FINDINGS: A genome-wide gene expression analysis was performed on a cohort of 91...

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