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Article

Association of clinico-genomic characteristics with tumor mutational burden in small cell lung cancer patients.

Future oncology (London, England) - 1 Feb 2021

Kachroo Sumesh, Shao Changxia, Desai Kaushal, He Jinghua, Jin Fan, Sen Shuvayu

Abstract excerpt

Aim: We evaluated the relationship between clinical and genomic characteristics and tumor mutational burden (TMB) in small cell lung cancer. Materials & methods: In a retrospective analysis of small cell lung cancer patients aged ≥18, we assessed treatment patterns and survival in relation to TMB; the association of clinical and genomic characteristics with TMB was determined by multivariate regression. High TMB...

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PMID: 33198513
DOI: 10.2217/fon-2020-0728

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