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Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology.

Communications biology - 21 Jun 2022

Ahmed Muktar, Mäkinen Ville-Petteri, Mulugeta Anwar, Shin Jisu, Boyle Terry, Hyppönen Elina, Lee Sang Hong

Abstract excerpt

Hormone-related cancers, including cancers of the breast, prostate, ovaries, uterine, and thyroid, globally contribute to the majority of cancer incidence. We hypothesize that hormone-sensitive cancers share common genetic risk factors that have rarely been investigated by previous genomic studies of site-specific cancers. Here, we show that considering hormone-sensitive cancers as a single disease in the UK...

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Identifiers

PMID: 35729236
DOI: 10.1038/s42003-022-03554-y
PMCID: PMC9213416

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