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Article

The c.612A>G mutation of MC4R affects constitutive activity and signaling in domestic goats.

Animal genetics - 1 Oct 2022

Yan Yinan, Chi Shaxuan, Liu Guiqiong, Huang Yongjie, Pan Dongmei, Jiang Xunping

Abstract excerpt

As a key gene for balancing energy and regulating feeding behavior, MC4R is relevant to the growth of ruminants. In this presentation, a highly conserved c.612A>G site in the coding sequence (CDS) of MC4R has been selected during a selective sweep analysis of 35 Yiling goats and 20 other wild goats. This site mutation results in an amino acid change from Ile to Met. The genotyping analysis of the c.612A>G site...

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PMID: 35727803
DOI: 10.1111/age.13214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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