Article
Optimization of initial dose regimen of tacrolimus in paediatric lung transplant recipients based on Monte Carlo simulation.
Journal of clinical pharmacy and therapeutics - 1 Oct 2022
Wang Dong-Dong, Mei Yu-Qing, Yang Lan, Ding Ke-Wen, Xue Jun-Jie, Wang Xuan, He Su-Mei, Wei Qun-Li
Abstract excerpt
WHAT IS KNOWN AND OBJECTIVES: The initial tacrolimus dose regimen in paediatric lung transplant recipients is unknown. The present study optimized the initial tacrolimus dose regimen for paediatric lung transplant recipients. METHODS: This study was based on a published population pharmacokinetic model of tacrolimus in lung transplant recipients and used Monte Carlo simulations to recommend an initial dose...
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