Article
Relation Between the Number of Peaks and the Number of Reciprocal Sign Epistatic Interactions.
Bulletin of mathematical biology - 17 Jun 2022
Saona Raimundo, Kondrashov Fyodor A, Khudiakova Ksenia A
Abstract excerpt
Empirical essays of fitness landscapes suggest that they may be rugged, that is having multiple fitness peaks. Such fitness landscapes, those that have multiple peaks, necessarily have special local structures, called reciprocal sign epistasis (Poelwijk et al. in J Theor Biol 272:141-144, 2011). Here, we investigate the quantitative relationship between the number of fitness peaks and the number of reciprocal...
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