Article
The rank ordering of genotypic fitness values predicts genetic constraint on natural selection on landscapes lacking sign epistasis.
Genetics - 1 Nov 2005
Weinreich Daniel M
Abstract excerpt
Sewall Wright's genotypic fitness landscape makes explicit one mechanism by which epistasis for fitness can constrain evolution by natural selection. Wright distinguished between landscapes possessing multiple fitness peaks and those with only a single peak and emphasized that the former class imposes substantially greater constraint on natural selection. Here I present novel formalism that more finely partitions...
Topics
Join the communities discussing this publication.