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Article

EDN1 Gene Variant is Associated with Neonatal Persistent Pulmonary Hypertension.

Scientific reports - 18 Jul 2016

Mei Mei, Cheng Guoqiang, Sun Bijun, Yang Lin, Wang Huijun, Sun Jinqiao, Zhou Wenhao

Abstract excerpt

Recent studies have suggested associations between certain genetic variants and susceptibility to persistent pulmonary hypertension of the newborn (PPHN). The aim of the study was to evaluate the association of EDN1, NOS3, ACE and VEGFA genes with PPHN. Neonates with respiratory distress were enrolled in the study, whose gestational age ≥34 weeks, age ≤3 days. They were divided into PPHN and non-PPHN group. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27425626
DOI: 10.1038/srep29877
PMCID: PMC4947908

Genes

EDN1
ACE
NOS3
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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