Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic analysis of right heart structure and function in 40,000 people

1 Jun 2022

Abstract excerpt

Congenital heart diseases often involve maldevelopment of the evolutionarily recent right heart chamber. To gain insight into right heart structure and function, we fine-tuned deep learning models to recognize the right atrium, right ventricle and pulmonary artery, measuring right heart structures in 40,000 individuals from the UK Biobank with magnetic resonance imaging. Genome-wide association studies identified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Congenital Heart Disease Studies
Share to Pulmonary Hypertension Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35697867
DOI: 10.1038/s41588-022-01090-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic analysis of right heart structure and function in 40,000 peoplePMID 35697867Read ↗

Genetic Analysis of Right Heart Structure and Function in 40,000 PeopleSemantic proximity Read ↗

Genetic regulation of right ventricular trabeculation identifies developmental and cardiopulmonary pathwaysSemantic proximity Read ↗

Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and functionSemantic proximity Read ↗

Sex-specific genetic determinants of right ventricular structure and functionSemantic proximity Read ↗

Genetic architecture of cardiac structure and functionSemantic proximity Read ↗

Using Machine Learning to Elucidate the Spatial and Genetic Complexity of the Ascending AortaSemantic proximity Read ↗

Genome-wide analysis of cardiac ventricular phenotypes reveals novel loci and therapeutic targets for heart failure.Semantic proximity Read ↗

Rare GATA6 variants associated with risk of congenital heart disease phenotypes in 200,000 UK Biobank exomes.Semantic proximity Read ↗

Genome-wide association analysis of left ventricular imaging-derived phenotypes identifies 72 risk loci and yields genetic insights into hypertrophic cardiomyopathy.Semantic proximity Read ↗

Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure DevelopmentSemantic proximity Read ↗

Multimodal Hypersampling of the adult human heart resolves tissue-specific cell states and disease-associated variantsSemantic proximity Read ↗

Genomic analysis reveals a functional role for myocardial trabeculae in adultsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.