Article
Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis.
Thorax - 1 Aug 2022
Allen Richard J, Stockwell Amy, Oldham Justin M, Guillen-Guio Beatriz, Schwartz David A, Maher Toby M, Flores Carlos, Noth Imre, Yaspan Brian L, Jenkins R Gisli, Wain Louise V
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a chronic lung condition with poor survival times. We previously published a genome-wide meta-analysis of IPF risk across three studies with independent replication of associated variants in two additional studies. To maximise power and to generate more accurate effect size estimates, we performed a genome-wide meta-analysis across all five studies included in the previous...
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