Article
Integrated analysis of genome-wide association studies and 3D epigenomic characteristics reveal the BMP2 gene regulating loin muscle depth in Yorkshire pigs.
PLoS genetics - 1 Jun 2023
Miao Yuanxin, Zhao Yunxia, Wan Siqi, Mei Quanshun, Wang Heng, Fu Chuanke, Li Xinyun, Zhao Shuhong, Xu Xuewen, Xiang Tao
Abstract excerpt
BACKGROUND: The lack of integrated analysis of genome-wide association studies (GWAS) and 3D epigenomics restricts a deep understanding of the genetic mechanisms of meat-related traits. With the application of techniques as ChIP-seq and Hi-C, the annotations of cis-regulatory elements in the pig genome have been established, which offers a new opportunity to elucidate the genetic mechanisms and identify major...
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