Article
Association between polymorphisms of ABCB1 and prognosis in esophageal squamous cell carcinoma patients treated with taxane.
The journal of gene medicine - 1 Jul 2022
Sun Zhiwei, Yang Xin, Du Feng, Shi Youwu, Sun Jing, Jia Jun, Liu Chuanling, Xiao Yanjie, Yu Jing, Zhang Xiaodong, Yang Ying
Abstract excerpt
BACKGROUND: In China, most esophageal cancer patients are squamous cell carcinomas and are treated with taxane-containing regimens; however, few studies have examined taxane pharmacokinetics genes and esophageal squamous cell carcinoma (ESCC) prognosis. METHODS: In total, 227 pathologically confirmed ESCC patients receiving chemotherapy with taxane were included in the analysis. We genotyped seven SNPs...
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