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Article

Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer.

Cancer - 1 Jul 2007

Han Ji-Youn, Lim Hyeong-Seok, Yoo Yeon-Kyeong, Shin Eun Soon, Park Yong Hoon, Lee Sung Young, Lee Jong-Eun, Lee Dea Ho, Kim Heung Tae, Lee Jin Soo

Abstract excerpt

BACKGROUND: The authors investigated whether ABCB1, ABCC2, and ABCG2 genetic polymorphisms affect pharmacokinetics (PK) of irinotecan and treatment outcome of patients with advanced nonsmall cell lung cancer (NSCLC). METHODS: Blood samples from 107 NSCLC patients treated with irinotecan and cispl...

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Source

Identifiers

PMID: 17534875
DOI: 10.1002/cncr.22760

Genes

ABCC2
ABCB1
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17534875-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer.PMID 17534875Read ↗

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