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hapln1 Defines an Epicardial Cell Subpopulation Required for Cardiomyocyte Expansion During Heart Morphogenesis and Regeneration

5 Jul 2022

Abstract excerpt

Background: Certain nonmammalian species such as zebrafish have an elevated capacity for innate heart regeneration. Understanding how heart regeneration occurs in these contexts can help illuminate cellular and molecular events that can be targets for heart failure prevention or treatment. The epicardium, a mesothelial tissue layer that encompasses the heart, is a dynamic structure that is essential for cardiac...

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PMID: 35652354
DOI: 10.1161/circulationaha.121.055468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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