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Article

BRAF, NRAS, KIT, TERT, GNAQ/GNA11 Mutation Profile and Histomorphological Analysis of Anorectal Melanomas: A Clinicopathologic Study.

Turk patoloji dergisi - 1 Jan 2023

Taskin Orhun Cig, Sari Sule Ozturk, Yilmaz Ismail, Hurdogan Ozge, Keskin Metin, Buyukbabani Nesimi, Gulluoglu Mine

Abstract excerpt

OBJECTIVE: Primary anorectal melanomas (AMs) are uncommon neoplasms with aggressive behavior. Molecular profile and clinicopathologic features of AMs are still not well established. In this study, we aimed to investigate BRAF, NRAS, KIT, TERT, and GNAQ/GNA11 mutation status and clinicopathologic features of AMs. MATERIAL AND METHOD: All diagnostic slides of 15 AMs were reviewed. Histopathological and follow-up...

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Identifiers

PMID: 35642348
DOI: 10.5146/tjpath.2022.01576
PMCID: PMC10518134

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