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Article

Clinical Significance of Gene Mutations and Polymorphic Variants and their Association with Prostate Cancer Risk in Polish Men.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000

Heise Marta, Jarzemski Piotr, Nowak Dagmara, Bąk Aneta, Junkiert-Czarnecka Anna, Pilarska-Deltow Maria, Borysiak Maciej, Pilarska Beata, Haus Olga

Abstract excerpt

Objectives: We tested the association of germline variants in BRCA1, BRCA2, CHEK2, CDKN2A, CYP1B1, HOXB13, MLH1, NBS1, NOD2 andPALB2 genes, as well as in 8q24 region, with prostate cancer (PC) risk and estimated their impact on disease clinical course, including overall survival time in Polish men with localized PC qualified for radical treatment.Materials and Methods: DNA of 110 patients with localized prostate...

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Identifiers

PMID: 35638715
DOI: 10.1177/10732748211062342
PMCID: PMC9160909

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