Article
Got your mother in a whirl: The role of maternal T cells and myeloid cells in pregnancy.
HLA - 1 Nov 2020
Eikmans Michael, van der Zwan Anita, Claas Frans H J, van der Hoorn Marie-Louise, Heidt Sebastiaan
Abstract excerpt
Appropriate development of the placenta is required for healthy pregnancy to occur. After implantation of the fertilized blastocyst, fetal trophoblasts invade the endometrium and myometrium of the mother's uterus to establish placentation. In this process, fetal trophoblasts encounter maternal immune cells. In this review, we focus on the role of maternal T cells and myeloid cells (macrophages, dendritic cells)...
Topics
- Alleles
- Female
- Humans
- Mothers
- Myeloid Cells
- Placenta
- Pregnancy
- T-Lymphocytes, Regulatory