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Article

High Expression of HERV-K (HML-2) Might Stimulate Interferon in COVID-19 Patients

7 May 2022

Abstract excerpt

Background. Interferon is a marker of host antiviral immunity, which is disordered in COVID-19 patients. ERV can affect the secretion of interferon through the cGAS-STING pathway. In this study, we explored whether IFN-I and HERV-K (HML-2) were activated in COVID-19 patients and whether there was an interaction between them. Methods. We collected blood samples from COVID-19 patients and healthy controls. We first...

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PMID: 35632738
DOI: 10.3390/v14050996

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