IFNL4 genetic variant can predispose to COVID-19.

doi:10.1038/s41598-021-00747-z

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Article

IFNL4 genetic variant can predispose to COVID-19.

Scientific reports - 27 Oct 2021

Saponi-Cortes Jose Maria R, Rivas Maria Dolores, Calle-Alonso Fernando, Sanchez Juan F, Costo Alberto, Martin Carlos, Zamorano Jose

Abstract excerpt

Interferon lambda 4 (IFNλ4) has shown antiviral activity against RNA viruses, including some coronaviruses. Besides, genetic variants of IFNL4 can be predictive of the clearance of RNA viruses. However, little is known about the effect of these genetic variants on SARS-CoV-2 infection. In this study, we investigated whether there was a relationship of the rs12979860 polymorphism of IFNL4 with COVID-19. We found...

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Identifiers

PMID: 34707167
DOI: 10.1038/s41598-021-00747-z
PMCID: PMC8551167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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