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Article

Flavivirus Capsid Proteins Inhibit the Interferon Response

5 May 2022

Abstract excerpt

Zika virus (ZIKV) establishes persistent infections in multiple human tissues, a phenomenon that likely plays a role in its ability to cause congenital birth defects and neurological disease. Multiple nonstructural proteins encoded by ZIKV, in particular NS5, are known to suppress the interferon (IFN) response by attacking different steps in this critical antiviral pathway. Less well known are the potential roles...

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PMID: 35632712
DOI: 10.3390/v14050968

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