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Article

Multimodal Functionalities of HIV-1 Integrase

28 Apr 2022

Abstract excerpt

Integrase is the retroviral protein responsible for integrating reverse transcripts into cellular genomes. Co-packaged with viral RNA and reverse transcriptase into capsid-encased viral cores, human immunodeficiency virus 1 (HIV-1) integrase has long been implicated in reverse transcription and virion maturation. However, the underlying mechanisms of integrase in these non-catalytic-related viral replication...

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PMID: 35632668
DOI: 10.3390/v14050926

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