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Article

Complex Mutation Pattern of Omicron BA.2: Evading Antibodies without Losing Receptor Interactions.

International journal of molecular sciences - 16 May 2022

Kannan Saathvik R, Spratt Austin N, Sharma Kalicharan, Goyal Ramesh, Sönnerborg Anders, Apparsundaram Subbu, Lorson Christian L, Byrareddy Siddappa N, Singh Kamal

Abstract excerpt

BA.2, a sublineage of Omicron BA.1, is now prominent in many parts of the world. Early reports have indicated that BA.2 is more infectious than BA.1. To gain insight into BA.2 mutation profile and the resulting impact of mutations on interactions with receptor and/or monoclonal antibodies, we analyzed available sequences, structures of Spike/receptor and Spike/antibody complexes, and conducted molecular dynamics...

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Identifiers

PMID: 35628343
DOI: 10.3390/ijms23105534
PMCID: PMC9141577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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