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Article

The Role of Functional Polymorphisms in the Extracellular Matrix Modulation-Related Genes on Dupuytren's Contracture.

Genes - 23 Apr 2022

Samulenas Gediminas, Insodaite Ruta, Kunceviciene Edita, Poceviciute Roberta, Masionyte Lorena, Zitkeviciute Urte, Pilipaityte Loreta, Smalinskiene Alina

Abstract excerpt

(1) Background: genetic variations, localized in the functional regions of the extracellular matrix (ECM) modulation-related genes, may alter the transcription process and impact the Dupuytren's contracture (DC). The present study investigated the association of single nucleotide polymorphisms (SNPs), localized in the functional regions of the MMP8, MMP14, and CHST6 genes, with DC risk. (2) Methods: we enrolled...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35627129
DOI: 10.3390/genes13050743
PMCID: PMC9141853

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