Article
Circulating microRNA-122 in HCV cirrhotic patients with high frequency of genotype 3.
PloS one - 1 Jan 2022
Ullah Amin, Yu Xiaojie, Odenthal Margarete, Meemboor Sonja, Ahmad Bashir, Rehman Irshad Ur, Ahmad Jamshaid, Ali Qurban, Nadeem Tariq
Abstract excerpt
MicroRNA-122 (miR-122) is a liver abundant microRNA that is released upon liver injury. In the present study, we investigated the circulating miR-122 profiles in a Pakistani patients´ cohort with HCV chronic liver disease that was mainly based on HCV genotype 3 infections. From 222 patients with chronic HCV liver disease, classified as mild, moderate, or severe, serum samples were collected. Cell-free RNA was...
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