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Article

Reduction of microRNA 122 expression in IFNL3 CT/TT carriers and during progression of fibrosis in patients with chronic hepatitis C.

Journal of virology - 1 Jun 2014

Estrabaud Emilie, Lapalus Martine, Broët Philippe, Appourchaux Kevin, De Muynck Simon, Lada Olivier, Martinot-Peignoux Michelle, Bièche Ivan, Valla Dominique, Bedossa Pierre, Marcellin Patrick, Vidaud Michel, Asselah Tarik

Abstract excerpt

UNLABELLED: The microRNA miR-122 is highly expressed in the liver and stimulates hepatitis C virus (HCV) replication in vitro. IFNL3 (lambda-3 interferon gene) polymorphisms and the expression of miR-122 have been associated with sustained virological response (SVR) to treatment with pegylated in...

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Source

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Identifiers

PMID: 24672032
DOI: 10.1128/JVI.00016-14
PMCID: PMC4093870

Genes

IFNL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24672032-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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