Article
Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis.
Journal of hepatology - 1 Feb 2013
Trebicka Jonel, Anadol Evrim, Elfimova Natalia, Strack Ingo, Roggendorf Michael, Viazov Sergei, Wedemeyer Inga, Drebber Uta, Rockstroh Jürgen, Sauerbruch Tilman, Dienes Hans-Peter, Odenthal Margarete
Abstract excerpt
BACKGROUND & AIMS: The progression of liver fibrosis in patients with chronic hepatitis C (CHC) is important to decide on the treatment of the virus. As liver biopsy and liver stiffness measurement for staging of fibrosis present limitations, circulating levels of miR-122 have been suggested as a novel biomarker to predict the extent of liver injury. We evaluated the potential of miR-122 as an indicator of...
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